| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-Serine/threonine-protein kinase Nek3 is suitable for use in Western Blot and ELISA research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-2000ELISA 1:5000-20000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | NEK3 |
| Gene ID: | 4752 |
| Uniprot ID: | NEK3_HUMAN |
| Specificity: | NEK3 Polyclonal Antibody detects endogenous levels of protein. |
| Immunogen: | Synthesized peptide derived from part of the human protein |
| Post Translational Modifications | Phosphorylation at Thr-479 regulates its catalytic activity. |
| Function | Protein kinase which influences neuronal morphogenesis and polarity through effects on microtubules. Regulates microtubule acetylation in neurons. Contributes to prolactin-mediated phosphorylation of PXN and VAV2. Implicated in prolactin-mediated cytoskeletal reorganization and motility of breast cancer cells through mechanisms involving RAC1 activation and phosphorylation of PXN and VAV2. |
| Protein Name | Serine/Threonine-Protein Kinase Nek3Hspk 36Never In Mitosis A-Related Kinase 3Nima-Related Protein Kinase 3 |
| Cellular Localisation | CytoplasmCell ProjectionAxon |
| Alternative Antibody Names | Anti-Serine/Threonine-Protein Kinase Nek3 antibodyAnti-Hspk 36 antibodyAnti-Never In Mitosis A-Related Kinase 3 antibodyAnti-Nima-Related Protein Kinase 3 antibodyAnti-NEK3 antibody |
Information sourced from Uniprot.org