Anti-NEK1 antibody (280-360 aa) (STJ191365)

SKU:
STJ191365
€60.00 - €315.00
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Host: Rabbit
Applications: WB/ELISA
Reactivity: Human/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Rabbit polyclonal antibody anti-Serine/threonine-protein kinase Nek1 (280-360 aa) is suitable for use in Western Blot and ELISA research applications.
Clonality : Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-2000
ELISA 1:5000-20000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: NEK1
Gene ID: 4750
Uniprot ID: NEK1_HUMAN
Immunogen Region: 280-360 aa
Specificity: NEK1 Polyclonal Antibody detects endogenous levels of protein.
Immunogen: Synthesized peptide derived from the human protein at the amino acid range 280-360
Function Phosphorylates serines and threonines, but also appears to possess tyrosine kinase activity. Involved in DNA damage checkpoint control and for proper DNA damage repair. In response to injury that includes DNA damage, NEK1 phosphorylates VDAC1 to limit mitochondrial cell death. May be implicated in the control of meiosis. Involved in cilium assembly.
Protein Name Serine/Threonine-Protein Kinase Nek1
Never In Mitosis A-Related Kinase 1
Nima-Related Protein Kinase 1
Renal Carcinoma Antigen Ny-Ren-55
Database Links Reactome: R-HSA-9861718
Cellular Localisation Nucleus
Cytoplasm
Cytoskeleton
Microtubule Organizing Center
Centrosome
Associated With The Pericentriolar Material
Localizes To Centrosome During Interphase And Mitosis
Translocated From Cytoplasm To Discrete Nuclear Foci At Sites Of Dna Damage
Alternative Antibody Names Anti-Serine/Threonine-Protein Kinase Nek1 antibody
Anti-Never In Mitosis A-Related Kinase 1 antibody
Anti-Nima-Related Protein Kinase 1 antibody
Anti-Renal Carcinoma Antigen Ny-Ren-55 antibody
Anti-NEK1 antibody
Anti-KIAA1901 antibody

Information sourced from Uniprot.org

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