Host: |
Rabbit |
Applications: |
WB/IHC/IF/ELISA |
Reactivity: |
Human/Mouse |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Rabbit polyclonal antibody anti-N-terminal EF-hand calcium-binding protein 3 (321-370 aa) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications. |
Clonality: |
Polyclonal |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Concentration: |
1 mg/mL |
Dilution Range: |
WB 1:500-1:2000IHC 1:100-1:300IF 1:200-1:1000ELISA 1:40000 |
Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: |
NECAB3 |
Gene ID: |
63941 |
Uniprot ID: |
NECA3_HUMAN |
Immunogen Region: |
321-370 aa |
Specificity: |
APBA2BP Polyclonal Antibody detects endogenous levels of APBA2BP protein. |
Immunogen: |
The antiserum was produced against synthesized peptide derived from the human NECAB3 at the amino acid range 321-370 |
Post Translational Modifications | Phosphorylated by NEK2. |
Function | Inhibits the interaction of APBA2 with amyloid-beta precursor protein (APP), and hence allows formation of amyloid-beta. May enhance the activity of HIF1A and thus promote glycolysis under normoxic conditions.the function requires its ABM domain and may implicate the stabilization of the interaction between HIF1AN and APBA3. |
Protein Name | N-Terminal Ef-Hand Calcium-Binding Protein 3Amyloid-Beta A4 Protein-Binding Family A Member 2-Binding ProteinNek2-Interacting Protein 1Neuronal Calcium-Binding Protein 3X11l-Binding Protein 51 |
Cellular Localisation | Golgi Apparatus |
Alternative Antibody Names | Anti-N-Terminal Ef-Hand Calcium-Binding Protein 3 antibodyAnti-Amyloid-Beta A4 Protein-Binding Family A Member 2-Binding Protein antibodyAnti-Nek2-Interacting Protein 1 antibodyAnti-Neuronal Calcium-Binding Protein 3 antibodyAnti-X11l-Binding Protein 51 antibodyAnti-NECAB3 antibodyAnti-APBA2BP antibodyAnti-NIP1 antibodyAnti-SYTIP2 antibodyAnti-XB51 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance