Anti-NECAB2 antibody (STJA0007358)

Name: Anti-NECAB2 antibody (STJA0007358)
SKU: STJA0007358
Availability: InStock

⇓ Datasheet ⇓ SDS

SPECIFICATIONS

ClonalityPolyclonal

HostRabbit

ConjugationUnconjugated

IsotypeIgG

ImmunogenSynthesized peptide derived from human NECAB2

STJA0007358

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Short Description	Rabbit polyclonal anti-N-terminal EF-hand calcium-binding protein 2 for use in WB in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents.
Applications	WB
Host	Rabbit
Reactivity	Human/Mouse
Note	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Clonality	Polyclonal
Isotype	IgG
Conjugation	Unconjugated
Concentration	1 mg/mL
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Dilution Range	WB 1:500-2000
Formulation	Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Storage Instruction	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Gene Symbol	NECAB2
Gene ID	54550
Uniprot ID	NECA2_HUMAN
Immunogen	Synthesized peptide derived from human NECAB2
Specificity	This antibody detects endogenous levels of NECAB2 at Human, Mouse

Function	May act as a signaling scaffold protein that senses intracellular calcium. Can modulate ligand-induced internalization of ADORA2A and coupling efficiency of mGluR5/GRM5.for both receptors may regulate signaling activity such as promoting MAPK1/3 (ERK1/2) activation.
Protein Name	N-Terminal Ef-Hand Calcium-Binding Protein 2 Ef-Hand Calcium-Binding Protein 2 Neuronal Calcium-Binding Protein 2 Synaptotagmin-Interacting Protein 2 Stip-2
Database Links
Cellular Localisation	Cytoplasm Cell Projection Dendrite Axon Cell Membrane Colocalizes With Adora2a And/Or Mglur5/Grm5 At The Plasma Membrane Found In Neuronal Somata Detected In The Cytoplasm Of Striatal Neurons At Postsynaptic Sites Filling Dendritic Shafts And Spines And At Presynaptic Sites Filling Axon Terminals
Alternative Antibody Names	Anti-N-Terminal Ef-Hand Calcium-Binding Protein 2 antibody Anti-Ef-Hand Calcium-Binding Protein 2 antibody Anti-Neuronal Calcium-Binding Protein 2 antibody Anti-Synaptotagmin-Interacting Protein 2 antibody Anti-Stip-2 antibody Anti-NECAB2 antibody Anti-EFCBP2 antibody

Information sourced from Uniprot.org