| Function | May act as a signaling scaffold protein that senses intracellular calcium. Can modulate ligand-induced internalization of ADORA2A and coupling efficiency of mGluR5/GRM5.for both receptors may regulate signaling activity such as promoting MAPK1/3 (ERK1/2) activation. |
| Protein Name | N-Terminal Ef-Hand Calcium-Binding Protein 2Ef-Hand Calcium-Binding Protein 2Neuronal Calcium-Binding Protein 2Synaptotagmin-Interacting Protein 2Stip-2 |
| Cellular Localisation | CytoplasmCell ProjectionDendriteAxonCell MembraneColocalizes With Adora2a And/Or Mglur5/Grm5 At The Plasma MembraneFound In Neuronal SomataDetected In The Cytoplasm Of Striatal NeuronsAt Postsynaptic SitesFilling Dendritic Shafts And SpinesAnd At Presynaptic SitesFilling Axon Terminals |
| Alternative Antibody Names | Anti-N-Terminal Ef-Hand Calcium-Binding Protein 2 antibodyAnti-Ef-Hand Calcium-Binding Protein 2 antibodyAnti-Neuronal Calcium-Binding Protein 2 antibodyAnti-Synaptotagmin-Interacting Protein 2 antibodyAnti-Stip-2 antibodyAnti-NECAB2 antibodyAnti-EFCBP2 antibody |
Information sourced from Uniprot.org
