| Short Description : | Rabbit polyclonal NDUFV1 (72-420) antibody for use in WB, IHC-P and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | WB/IHC-P/ELISA |
| Host: | Rabbit |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | Lot specific |
| Purification: | Affinity purification |
| Dilution Range: | WB:1:500-1:1000IHC-P:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation: | PBS with 0.05% Proclin300, 50% Glycerol, pH 7.3. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | NDUFV1 |
| Gene ID: | 4723 |
| Uniprot ID: | NDUV1_HUMAN |
| Immunogen Region: | 72-420 |
| Immunogen Sequence: | GPDWILGEIKTSGLRGRGGA GFPTGLKWSFMNKPSDGRPK YLVVNADEGEPGTCKDREIL RHDPHKLLEGCLVGGRAMGA RAAYIYIRGEFYNEASNLQV AIREAYEAGLIGKNACGSGY DFDVFVVRGAGAYICGEETA LIESIEGKQGKPRLKPPFPA DVGVFGCPTTVANVETVAVS PTICRRGGTWFAGFGRERNS GTKLFNISGHVNHPCTVEEE MSVPLKELIEKHAGGVTGG |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 72-420 of human NDUFV1 (NP_009034.2). |
| Function | Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor. Part of the peripheral arm of the enzyme, where the electrons from NADH are accepted by flavin mononucleotide (FMN) and then passed along a chain of iron-sulfur clusters by electron tunnelling to the final acceptor ubiquinone. Contains FMN, which is the initial electron acceptor as well as one iron-sulfur cluster. |
| Protein Name | Nadh Dehydrogenase Ubiquinone Flavoprotein 1 - MitochondrialNdufv1Complex I-51kdCi-51kdNadh Dehydrogenase Flavoprotein 1Nadh-Ubiquinone Oxidoreductase 51 Kda Subunit |
| Database Links | Reactome: R-HSA-611105Reactome: R-HSA-6799198Reactome: R-HSA-9837999 |
| Cellular Localisation | Mitochondrion Inner MembranePeripheral Membrane ProteinMatrix Side |
| Alternative Antibody Names | Anti-Nadh Dehydrogenase Ubiquinone Flavoprotein 1 - Mitochondrial antibodyAnti-Ndufv1 antibodyAnti-Complex I-51kd antibodyAnti-Ci-51kd antibodyAnti-Nadh Dehydrogenase Flavoprotein 1 antibodyAnti-Nadh-Ubiquinone Oxidoreductase 51 Kda Subunit antibodyAnti-NDUFV1 antibodyAnti-UQOR1 antibody |
Information sourced from Uniprot.org

