| Host: | Rabbit |
| Applications: | WB/IP/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000IP:0.5 Mu g-4 Mu g antibody for 400 Mu g-600 Mu g extracts of whole cellsELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | NDUFS3 |
| Gene ID: | 4722 |
| Uniprot ID: | NDUS3_HUMAN |
| Immunogen Region: | 37-264 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 37-264 of human NDUFS3 (NP_004542.1). |
| Immunogen Sequence: | ESAGADTRPTVRPRNDVAHK QLSAFGEYVAEILPKYVQQV QVSCFNELEVCIHPDGVIPV LTFLRDHTNAQFKSLVDLTA VDVPTRQNRFEIVYNLLSLR FNSRIRVKTYTDELTPIESA VSVFKAANWYEREIWDMFGV FFANHPDLRRILTDYGFEGH PFRKDFPLSGYVELRYDDEV KRVVAEPVELAQEFRKFDLN SPWEAFPVYRQPPESLKLEA GDKKPDAK |
| Function | Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor. Essential for the catalytic activity and assembly of complex I. |
| Protein Name | Nadh Dehydrogenase Ubiquinone Iron-Sulfur Protein 3 - MitochondrialComplex I-30kdCi-30kdNadh-Ubiquinone Oxidoreductase 30 Kda Subunit |
| Database Links | Reactome: R-HSA-611105Reactome: R-HSA-6799198Reactome: R-HSA-9013408Reactome: R-HSA-9837999 |
| Cellular Localisation | Mitochondrion Inner MembranePeripheral Membrane ProteinMatrix Side |
| Alternative Antibody Names | Anti-Nadh Dehydrogenase Ubiquinone Iron-Sulfur Protein 3 - Mitochondrial antibodyAnti-Complex I-30kd antibodyAnti-Ci-30kd antibodyAnti-Nadh-Ubiquinone Oxidoreductase 30 Kda Subunit antibodyAnti-NDUFS3 antibody |
Information sourced from Uniprot.org