| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-NDUFA10 (36-300) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:1000-1:4000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
NDUFA10 |
| Gene ID: |
4705 |
| Uniprot ID: |
NDUAA_HUMAN |
| Immunogen Region: |
36-300 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 36-300 of human NDUFA10 (NP_004535.1). |
| Immunogen Sequence: |
LRYGMWHFLLGDKASKRLTE RSRVITVDGNICTGKGKLAK EIAEKLGFKHFPEAGIHYPD STTGDGKPLATDYNGNCSLE KFYDDPRSNDGNSYRLQSWL YSSRLLQYSDALEHLLTTGQ GVVLERSIFSDFVFLEAMYN QGFIRKQCVDHYNEVKSVTI CDYLPPHLVIYIDVPVPEVQ RRIQKKGDPHEMKITSAYLQ DIENAYKKTFLPEMSEKCEV LQYSAREAQDSKKVVEDIE |
| Post Translational Modifications | Phosphorylation at Ser-250 by PINK1 is required for the binding and/or reduction of the complex I substrate ubiquinone. |
| Function | Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. |
| Protein Name | Nadh Dehydrogenase Ubiquinone 1 Alpha Subcomplex Subunit 10 - MitochondrialComplex I-42kdCi-42kdNadh-Ubiquinone Oxidoreductase 42 Kda Subunit |
| Database Links | Reactome: R-HSA-611105Reactome: R-HSA-6799198 |
| Cellular Localisation | Mitochondrion Matrix |
| Alternative Antibody Names | Anti-Nadh Dehydrogenase Ubiquinone 1 Alpha Subcomplex Subunit 10 - Mitochondrial antibodyAnti-Complex I-42kd antibodyAnti-Ci-42kd antibodyAnti-Nadh-Ubiquinone Oxidoreductase 42 Kda Subunit antibodyAnti-NDUFA10 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
