| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:1000-1:4000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | NDUFA10 |
| Gene ID: | 4705 |
| Uniprot ID: | NDUAA_HUMAN |
| Immunogen Region: | 36-300 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 36-300 of human NDUFA10 (NP_004535.1). |
| Immunogen Sequence: | LRYGMWHFLLGDKASKRLTE RSRVITVDGNICTGKGKLAK EIAEKLGFKHFPEAGIHYPD STTGDGKPLATDYNGNCSLE KFYDDPRSNDGNSYRLQSWL YSSRLLQYSDALEHLLTTGQ GVVLERSIFSDFVFLEAMYN QGFIRKQCVDHYNEVKSVTI CDYLPPHLVIYIDVPVPEVQ RRIQKKGDPHEMKITSAYLQ DIENAYKKTFLPEMSEKCEV LQYSAREAQDSKKVVEDIE |
| Post Translational Modifications | Phosphorylation at Ser-250 by PINK1 is required for the binding and/or reduction of the complex I substrate ubiquinone. |
| Function | Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. |
| Protein Name | Nadh Dehydrogenase Ubiquinone 1 Alpha Subcomplex Subunit 10 - MitochondrialComplex I-42kdCi-42kdNadh-Ubiquinone Oxidoreductase 42 Kda Subunit |
| Database Links | Reactome: R-HSA-611105Reactome: R-HSA-6799198 |
| Cellular Localisation | Mitochondrion Matrix |
| Alternative Antibody Names | Anti-Nadh Dehydrogenase Ubiquinone 1 Alpha Subcomplex Subunit 10 - Mitochondrial antibodyAnti-Complex I-42kd antibodyAnti-Ci-42kd antibodyAnti-Nadh-Ubiquinone Oxidoreductase 42 Kda Subunit antibodyAnti-NDUFA10 antibody |
Information sourced from Uniprot.org