Anti-NCOA5 antibody (345-394) (STJ94362)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenThe antiserum was produced against synthesized peptide derived from human NCOA5. AA range:345-394
General Information
| Short Description | Rabbit polyclonal anti-Nuclear receptor coactivator 5 (345-394) for use in IHC, IF and ELISA in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | IHC/IF/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | IHC 1:100-1:300ELISA 1:10000IF 1:50-200 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | NCOA5 |
| Gene ID | 57727 |
| Uniprot ID | NCOA5_HUMAN |
| Immunogen | The antiserum was produced against synthesized peptide derived from human NCOA5. AA range:345-394 |
| Immunogen Region | 345-394 |
| Specificity | NCoA-5 Polyclonal Antibody detects endogenous levels of NCoA-5 protein. |
Additional Info
| Tissue Specificity | Widely expressed. |
| Function | Nuclear receptor coregulator that can have both coactivator and corepressor functions. Interacts with nuclear receptors for steroids (ESR1 and ESR2) independently of the steroid binding domain (AF-2) of the ESR receptors, and with the orphan nuclear receptor NR1D2. Involved in the coactivation of nuclear steroid receptors (ER) as well as the corepression of MYC in response to 17-beta-estradiol (E2). |
| Protein Name | Nuclear Receptor Coactivator 5Ncoa-5Coactivator Independent Of Af-2Cia |
| Database Links | |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Nuclear Receptor Coactivator 5 antibodyAnti-Ncoa-5 antibodyAnti-Coactivator Independent Of Af-2 antibodyAnti-Cia antibodyAnti-NCOA5 antibodyAnti-KIAA1637 antibody |
Information sourced from Uniprot.org