| Host: |
Rabbit |
| Applications: |
WB/ELISA |
| Reactivity: |
Human/Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-NCK-interacting protein with SH3 domain is suitable for use in Western Blot and ELISA research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide. |
| Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: |
1 mg/mL |
| Dilution Range: |
WB 1:500-2000ELISA 1:5000-20000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
NCKIPSD |
| Gene ID: |
51517 |
| Uniprot ID: |
SPN90_HUMAN |
| Specificity: |
SPN90 Polyclonal Antibody detects endogenous levels of protein. |
| Immunogen: |
Synthesized peptide derived from part of the human protein |
| Function | Has an important role in stress fiber formation induced by active diaphanous protein homolog 1 (DRF1). Induces microspike formation, in vivo. In vitro, stimulates N-WASP-induced ARP2/3 complex activation in the absence of CDC42. May play an important role in the maintenance of sarcomeres and/or in the assembly of myofibrils into sarcomeres. Implicated in regulation of actin polymerization and cell adhesion. Plays a role in angiogenesis. |
| Protein Name | Nck-Interacting Protein With Sh3 Domain54 Kda Vaca-Interacting Protein54 Kda Vimentin-Interacting ProteinVip5490 Kda Sh3 Protein Interacting With NckAf3p21Dia-Interacting Protein 1Dip-1Diaphanous Protein-Interacting ProteinSh3 Adapter Protein Spin90Wasp-Interacting Sh3-Domain ProteinWishWiskott-Aldrich Syndrome Protein-Interacting Protein |
| Database Links | Reactome: R-HSA-2029482Reactome: R-HSA-5663213Reactome: R-HSA-9664422 |
| Cellular Localisation | NucleusColocalizes With Drf1 At Membrane RufflesAnd With Nck At Z-Disks In Mature Cardiac Myocytes |
| Alternative Antibody Names | Anti-Nck-Interacting Protein With Sh3 Domain antibodyAnti-54 Kda Vaca-Interacting Protein antibodyAnti-54 Kda Vimentin-Interacting Protein antibodyAnti-Vip54 antibodyAnti-90 Kda Sh3 Protein Interacting With Nck antibodyAnti-Af3p21 antibodyAnti-Dia-Interacting Protein 1 antibodyAnti-Dip-1 antibodyAnti-Diaphanous Protein-Interacting Protein antibodyAnti-Sh3 Adapter Protein Spin90 antibodyAnti-Wasp-Interacting Sh3-Domain Protein antibodyAnti-Wish antibodyAnti-Wiskott-Aldrich Syndrome Protein-Interacting Protein antibodyAnti-NCKIPSD antibodyAnti-AF3P21 antibodyAnti-SPIN90 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
