• Immunohistochemistry analysis of paraffin-embedded human colon carcinoma tissue, using NCK2 Antibody. The picture on the right is blocked with the synthesized peptide.

Anti-NCK2 antibody (331-380) (STJ94356)

SKU:
STJ94356

£46.00 - £226.00
Current Stock:
Host: Rabbit
Applications: IHC/IF/ELISA
Reactivity: Human/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Cytoplasmic protein NCK2 (331-380) is suitable for use in Immunohistochemistry, Immunofluorescence and ELISA research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: IHC 1:100-1:300
ELISA 1:10000
IF 1:50-200
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: NCK2
Gene ID: 8440
Uniprot ID: NCK2_HUMAN
Immunogen Region: 331-380
Specificity: Nck-2 Polyclonal Antibody detects endogenous levels of Nck-2 protein.
Immunogen: The antiserum was produced against synthesized peptide derived from human NCK2. AA range:331-380
Tissue Specificity Ubiquitous.
Post Translational Modifications Phosphorylated.
Function Adapter protein which associates with tyrosine-phosphorylated growth factor receptors or their cellular substrates. Maintains low levels of EIF2S1 phosphorylation by promoting its dephosphorylation by PP1. Plays a role in ELK1-dependent transcriptional activation in response to activated Ras signaling.
Protein Name Cytoplasmic Protein Nck2
Growth Factor Receptor-Bound Protein 4
Nck Adaptor Protein 2
Nck-2
Sh2/Sh3 Adaptor Protein Nck-Beta
Database Links Reactome: R-HSA-186763
Reactome: R-HSA-373753
Reactome: R-HSA-3928664
Reactome: R-HSA-428540
Reactome: R-HSA-4420097
Reactome: R-HSA-8985801
Reactome: R-HSA-9013420
Reactome: R-HSA-9013424
Cellular Localisation Cytoplasm
Endoplasmic Reticulum
Alternative Antibody Names Anti-Cytoplasmic Protein Nck2 antibody
Anti-Growth Factor Receptor-Bound Protein 4 antibody
Anti-Nck Adaptor Protein 2 antibody
Anti-Nck-2 antibody
Anti-Sh2/Sh3 Adaptor Protein Nck-Beta antibody
Anti-NCK2 antibody
Anti-GRB4 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance