| Host: | Rabbit |
| Applications: | IHC/IF |
| Reactivity: | Human/Rat/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-NBAS subunit of NRZ tethering complex (1880-1960 aa) is suitable for use in Immunohistochemistry and Immunofluorescence research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | IHC-P 1:50-300IF 1:50-200 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | NBAS |
| Gene ID: | 51594 |
| Uniprot ID: | NBAS_HUMAN |
| Immunogen Region: | 1880-1960 aa |
| Specificity: | NBAS Polyclonal Antibody detects endogenous levels of protein. |
| Immunogen: | Synthesized peptide derived from the human protein at the amino acid range 1880-1960 |
| Function | Involved in Golgi-to-endoplasmic reticulum (ER) retrograde transport.the function is proposed to depend on its association in the NRZ complex which is believed to play a role in SNARE assembly at the ER. Required for normal embryonic development. May play a role in the nonsense-mediated decay pathway of mRNAs containing premature stop codons. |
| Protein Name | Nbas Subunit Of Nrz Tethering ComplexNeuroblastoma-Amplified Gene ProteinNeuroblastoma-Amplified Sequence |
| Database Links | Reactome: R-HSA-6811434 |
| Cellular Localisation | CytoplasmEndoplasmic ReticulumEndoplasmic Reticulum MembranePeripheral Membrane Protein |
| Alternative Antibody Names | Anti-Nbas Subunit Of Nrz Tethering Complex antibodyAnti-Neuroblastoma-Amplified Gene Protein antibodyAnti-Neuroblastoma-Amplified Sequence antibodyAnti-NBAS antibodyAnti-NAG antibody |
Information sourced from Uniprot.org
