| Tissue Specificity | Ubiquitous. Biallelically expressed in fetal and adult tissues. Highest levels in testis. |
| Post Translational Modifications | Phosphorylated at the G0/G1 boundary but it is not phosphorylated in S-phase. Phosphorylated protein remains in the cytoplasm in a complex with histones during the G0/G1 transition, whereas dephosphorylation triggers its transport into the nucleus at the G1/S-boundary. Polyglutamylated by TTLL4, a modification that occurs exclusively on glutamate residues and results in polyglutamate chains on the gamma-carboxyl group. Some residues may also be monoglycylated but not polyglycylated due to the absence of functional TTLL10 in human. |
| Function | Acts as a histone chaperone in nucleosome assembly. |
| Protein Name | Nucleosome Assembly Protein 1-Like 4Nucleosome Assembly Protein 2Nap-2 |
| Cellular Localisation | NucleusCytoplasmPresent In The Cytoplasm And Excluded From The Nucleus During G0/G1 PhaseThen Relocates To The Nucleus By The Time Cells Are In S PhasePhosphorylated Form Localizes In The Cytoplasm During The G0/G1 TransitionWhereas Dephosphorylation Leads To Relocalization Into The Nucleus At The G1/S-Boundary |
| Alternative Antibody Names | Anti-Nucleosome Assembly Protein 1-Like 4 antibodyAnti-Nucleosome Assembly Protein 2 antibodyAnti-Nap-2 antibodyAnti-NAP1L4 antibodyAnti-NAP2 antibody |
Information sourced from Uniprot.org
