| Host: | Rabbit |
| Applications: | WB/ELISA/IHC |
| Reactivity: | Human/Rat/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-Nanos homolog 1 (151-200 aa) is suitable for use in Western Blot, ELISA and Immunohistochemistry research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-2000IHC-P 1:50-300ELISA 2000-20000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | NANOS1 |
| Gene ID: | 340719 |
| Uniprot ID: | NANO1_HUMAN |
| Immunogen Region: | 151-200 aa |
| Specificity: | Nanos Homologue 1 (NANOS1) Polyclonal Antibody detects endogenous levels of Nanos Homologue 1 (NANOS1) |
| Immunogen: | Synthesized peptide derived from Nanos Homologue 1 (NANOS1) at the amino acid range 151-200 |
| Function | May act as a translational repressor which regulates translation of specific mRNAs by forming a complex with PUM2 that associates with the 3'-UTR of mRNA targets. Capable of interfering with the proadhesive and anti-invasive functions of E-cadherin. Up-regulates the production of MMP14 to promote tumor cell invasion. |
| Protein Name | Nanos Homolog 1Nos-1Ec_rep1a |
| Cellular Localisation | CytoplasmPerinuclear RegionColocalizes With Snapin And Pum2 In The Perinuclear Region Of Germ Cells |
| Alternative Antibody Names | Anti-Nanos Homolog 1 antibodyAnti-Nos-1 antibodyAnti-Ec_rep1a antibodyAnti-NANOS1 antibodyAnti-NOS1 antibody |
Information sourced from Uniprot.org