Anti-NAGK antibody (STJA0010222)

SKU:
STJA0010222

Current Stock:
Host: Rabbit
Applications: WB/ELISA
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-N-acetyl-D-glucosamine kinase is suitable for use in Western Blot and ELISA research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:1000-2000
ELISA 1:5000-20000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: NAGK
Gene ID: 55577
Uniprot ID: NAGK_HUMAN
Specificity: This antibody detects endogenous levels of Human, Mouse, Rat NAGK
Immunogen: Synthesized peptide derived from human NAGK
Function Converts endogenous N-acetylglucosamine (GlcNAc), a major component of complex carbohydrates, from lysosomal degradation or nutritional sources into GlcNAc 6-phosphate. Involved in the N-glycolylneuraminic acid (Neu5Gc) degradation pathway: although human is not able to catalyze formation of Neu5Gc due to the inactive CMAHP enzyme, Neu5Gc is present in food and must be degraded. Also has N-acetylmannosamine (ManNAc) kinase activity. Also involved in innate immunity by promoting detection of bacterial peptidoglycan by NOD2: acts by catalyzing phosphorylation of muramyl dipeptide (MDP), a fragment of bacterial peptidoglycan, to generate 6-O-phospho-muramyl dipeptide, which acts as a direct ligand for NOD2.
Protein Name N-Acetyl-D-Glucosamine Kinase
N-Acetylglucosamine Kinase
Glcnac Kinase
Muramyl Dipeptide Kinase
N-Acetyl-D-Mannosamine Kinase
Database Links Reactome: R-HSA-446210
Alternative Antibody Names Anti-N-Acetyl-D-Glucosamine Kinase antibody
Anti-N-Acetylglucosamine Kinase antibody
Anti-Glcnac Kinase antibody
Anti-Muramyl Dipeptide Kinase antibody
Anti-N-Acetyl-D-Mannosamine Kinase antibody
Anti-NAGK antibody

Information sourced from Uniprot.org

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