| Short Description : | Rabbit polyclonal NAF1 (150-400) antibody for use in WB and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | WB/ELISA |
| Host: | Rabbit |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | Lot specific |
| Purification: | Affinity purification |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | NAF1 |
| Gene ID: | 92345 |
| Uniprot ID: | NAF1_HUMAN |
| Immunogen Region: | 150-400 |
| Immunogen Sequence: | PPVLSDGDDDLQIEKENKNF PLKTKDELLLNELPSVEELT IILPEDIELKPLGMVSSIIE QLVIIESMTNLPPVNEETVI FKSDRQAAGKIFEIFGPVAH PFYVLRFNSSDHIESKGIKI KETMYFAPSMKDFTQYIFTE KLKQDKGSDASWKNDQEPPP EALDFSDDEKEKEAKQRKKS QIQGRKKLKSEFNEPGEDFT EVHQNWNAHSSASEHAKGYR NREFTRGFSRARYPRSCHG |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 150-400 of human NAF1 (NP_612395.2). |
| Function | RNA-binding protein required for the maturation of box H/ACA snoRNPs complex and ribosome biogenesis. During assembly of the H/ACA snoRNPs complex, it associates with the complex and disappears during maturation of the complex and is replaced by NOLA1/GAR1 to yield mature H/ACA snoRNPs complex. Probably competes with NOLA1/GAR1 for binding with DKC1/NOLA4. |
| Protein Name | H/Aca Ribonucleoprotein Complex Non-Core Subunit Naf1Hnaf1 |
| Database Links | |
| Cellular Localisation | CytoplasmNucleusShuttles Between The Cytoplasm And The NucleusAbsent From The Nucleolus |
| Alternative Antibody Names | Anti-H/Aca Ribonucleoprotein Complex Non-Core Subunit Naf1 antibodyAnti-Hnaf1 antibodyAnti-NAF1 antibody |
Information sourced from Uniprot.org
