| Host: |
Goat |
| Applications: |
Pep-ELISA/WB |
| Reactivity: |
Human/Dog |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Goat polyclonal antibody anti-NAC1/BTBD14B (Internal) is suitable for use in ELISA and Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Purification: |
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Concentration: |
0.5 mg/mL |
| Dilution Range: |
Peptide ELISA: antibody detection limit dilution 1:2000.WB: Approx 55kDa band observed in Human Bone Marrow lysates (calculated MW of 57.3kDa according to NP_443108.1). Recommended concentration: 0.5-1.5µg/ml. |
| Storage Instruction: |
Store at-20°C on receipt and minimise freeze-thaw cycles. |
| Gene Symbol: |
NACC1 |
| Gene ID: |
112939 |
| Uniprot ID: |
NACC1_HUMAN |
| Immunogen Region: |
Internal |
| Accession Number: |
NP_443108.1 |
| Immunogen Sequence: |
KTEQQESDSVQC |
| Function | Functions as a transcriptional repressor. Seems to function as a transcriptional corepressor in neuronal cells through recruitment of HDAC3 and HDAC4. Contributes to tumor progression, and tumor cell proliferation and survival. This may be mediated at least in part through repressing transcriptional activity of GADD45GIP1. Required for recruiting the proteasome from the nucleus to the cytoplasm and dendritic spines. |
| Protein Name | Nucleus Accumbens-Associated Protein 1Nac-1Btb/Poz Domain-Containing Protein 14b |
| Cellular Localisation | NucleusCytoplasmDistribution In The Cytoplasm Is Dependent On Phosphorylation |
| Alternative Antibody Names | Anti-Nucleus Accumbens-Associated Protein 1 antibodyAnti-Nac-1 antibodyAnti-Btb/Poz Domain-Containing Protein 14b antibodyAnti-NACC1 antibodyAnti-BTBD14B antibodyAnti-NAC1 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
