| Host: | Rabbit |
| Applications: | WB/IHC/IF/ELISA |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-NGFI-A-binding protein 2 (261-310) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-1:2000IHC 1:100-1:300ELISA 1:10000IF 1:50-200 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | NAB2 |
| Gene ID: | 4665 |
| Uniprot ID: | NAB2_HUMAN |
| Immunogen Region: | 261-310 |
| Specificity: | NAB2 Polyclonal Antibody detects endogenous levels of NAB2 protein. |
| Immunogen: | The antiserum was produced against synthesized peptide derived from human NAB2. AA range:261-310 |
| Tissue Specificity | Widely expressed at low levels. Highly expressed in melanoma cell lines. |
| Post Translational Modifications | Sumoylation by EGR2 represses EGR2 transcriptional activity in hindbrain. |
| Function | Acts as a transcriptional repressor for zinc finger transcription factors EGR1 and EGR2. Isoform 2 lacks repression ability. |
| Protein Name | Ngfi-A-Binding Protein 2Egr-1-Binding Protein 2Melanoma-Associated Delayed Early Response ProteinProtein Mader |
| Database Links | Reactome: R-HSA-9031628Reactome: R-HSA-9619665 |
| Cellular Localisation | NucleusIsoform 2 Is Not Localized To The Nucleus |
| Alternative Antibody Names | Anti-Ngfi-A-Binding Protein 2 antibodyAnti-Egr-1-Binding Protein 2 antibodyAnti-Melanoma-Associated Delayed Early Response Protein antibodyAnti-Protein Mader antibodyAnti-NAB2 antibodyAnti-MADER antibody |
Information sourced from Uniprot.org