| Short Description : | Mouse monoclonal anti-Na+/K+ ATPase Beta 3 (ECD) for use in ELISA, WB, ICC and IP in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | ELISA/WB/ICC/IP |
| Host: | Mouse |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Monoclonal |
| Clone ID : | M016 |
| Isotype: | IgG1 |
| Conjugation: | Unconjugated |
| Purification: | Protein G Purified |
| Dilution Range: | WB 1:1000ICC 1:50IP 1:50 |
| Formulation: | PBS + 1 mg/ml BSA, 0.05% NaN3 and 50% glycerol |
| Storage Instruction: | Storage at-20°C is recommended, as aliquots may be taken without freeze/thawing due to presence of 50% glycerol. Stable for at least 1 year at-20°C. |
| Gene Symbol: | ATP1B3 |
| Gene ID: | 483 |
| Uniprot ID: | AT1B3_HUMAN |
| Immunogen: | Clone (M016) was generated from a proprietary antigen related to the native human Na+/K+ ATPase Beta 3 subunit expressed in A431 epidermoid carcinoma cell line. |
| Immunogen Region: | ECD |
| Immunogen Sequence: | Human |
| Specificity: | Clone M016 mouse monoclonal antibody detects a 40 kDa* protein on SDS-PAGE Native" immunoblots of human A431, LNCaP, MeWo, MDA-MB-231, and MCF7 cells. This antibody does not detect denatured Na+/K+ ATPase Beta 3 subunit. In addition, mass spectrometr |
| Function | This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. The exact function of the beta-3 subunit is not known. |
| Protein Name | Sodium/Potassium-Transporting Atpase Subunit Beta-3Sodium/Potassium-Dependent Atpase Subunit Beta-3Atpb-3Cd Antigen Cd298 |
| Database Links | Reactome: R-HSA-210991Reactome: R-HSA-5578775Reactome: R-HSA-936837Reactome: R-HSA-9679191 |
| Cellular Localisation | Apical Cell MembraneSingle-Pass Type Ii Membrane ProteinBasolateral Cell MembraneMelanosomeIdentified By Mass Spectrometry In Melanosome Fractions From Stage I To Stage Iv |
| Alternative Antibody Names | Anti-Sodium/Potassium-Transporting Atpase Subunit Beta-3 antibodyAnti-Sodium/Potassium-Dependent Atpase Subunit Beta-3 antibodyAnti-Atpb-3 antibodyAnti-Cd Antigen Cd298 antibodyAnti-ATP1B3 antibody |
Information sourced from Uniprot.org
