Anti-MYOZ2 antibody (1-264) (STJ28551)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal MYOZ2 (1-264) antibody for use in WB, IF, ICC and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IF/ICC/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000IF/ICC:1:50-1:100ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | MYOZ2 |
| Gene ID | 51778 |
| Uniprot ID | MYOZ2_HUMAN |
| Immunogen Region | 1-264 |
| Immunogen Sequence | MLSHNTMMKQRKQQATAIMK EVHGNDVDGMDLGKKVSIPR DIMLEELSHLSNRGARLFKM RQRRSDKYTFENFQYQSRAQ INHSIAMQNGKVDGSNLEGG SQQAPLTPPNTPDPRSPPNP DNIAPGYSGPLKEIPPEKFN TTAVPKYYQSPWEQAISNDP ELLEALYPKLFKPEGKAELP DYRSFNRVATPFGGFEKASR MVKFKVPDFELLLLTDPRFM SFVNPLSGRRSFNRTPKGW |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 1-264 of human MYOZ2 (NP_057683.1). |
Additional Info
| Tissue Specificity | Expressed specifically in heart and skeletal muscle. |
| Function | Myozenins may serve as intracellular binding proteins involved in linking Z line proteins such as alpha-actinin, gamma-filamin, TCAP/telethonin, LDB3/ZASP and localizing calcineurin signaling to the sarcomere. Plays an important role in the modulation of calcineurin signaling. May play a role in myofibrillogenesis. |
| Protein Name | Myozenin-2Calsarcin-1Fatz-Related Protein 2 |
| Database Links | |
| Cellular Localisation | CytoplasmMyofibrilSarcomereZ LineColocalizes With Actn1 And Ppp3ca At The Z-Line Of Heart And Skeletal Muscle |
| Alternative Antibody Names | Anti-Myozenin-2 antibodyAnti-Calsarcin-1 antibodyAnti-Fatz-Related Protein 2 antibodyAnti-MYOZ2 antibodyAnti-C4orf5 antibody |
Information sourced from Uniprot.org