| Host: | Rabbit |
| Applications: | WB/IF/ICC/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000 IF/ICC:1:50-1:100 ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | MYOZ2 |
| Gene ID: | 51778 |
| Uniprot ID: | MYOZ2_HUMAN |
| Immunogen Region: | 1-264 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-264 of human MYOZ2 (NP_057683.1). |
| Immunogen Sequence: | MLSHNTMMKQRKQQATAIMK EVHGNDVDGMDLGKKVSIPR DIMLEELSHLSNRGARLFKM RQRRSDKYTFENFQYQSRAQ INHSIAMQNGKVDGSNLEGG SQQAPLTPPNTPDPRSPPNP DNIAPGYSGPLKEIPPEKFN TTAVPKYYQSPWEQAISNDP ELLEALYPKLFKPEGKAELP DYRSFNRVATPFGGFEKASR MVKFKVPDFELLLLTDPRFM SFVNPLSGRRSFNRTPKGW |
| Tissue Specificity | Expressed specifically in heart and skeletal muscle. |
| Function | Myozenins may serve as intracellular binding proteins involved in linking Z line proteins such as alpha-actinin, gamma-filamin, TCAP/telethonin, LDB3/ZASP and localizing calcineurin signaling to the sarcomere. Plays an important role in the modulation of calcineurin signaling. May play a role in myofibrillogenesis. |
| Protein Name | Myozenin-2 Calsarcin-1 Fatz-Related Protein 2 |
| Cellular Localisation | Cytoplasm Myofibril Sarcomere Z Line Colocalizes With Actn1 And Ppp3ca At The Z-Line Of Heart And Skeletal Muscle |
| Alternative Antibody Names | Anti-Myozenin-2 antibody Anti-Calsarcin-1 antibody Anti-Fatz-Related Protein 2 antibody Anti-MYOZ2 antibody Anti-C4orf5 antibody |
Information sourced from Uniprot.org