| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-MYO18B (120-420) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
MYO18B |
| Gene ID: |
84700 |
| Uniprot ID: |
MY18B_HUMAN |
| Immunogen Region: |
120-420 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 120-420 of human MYO18B (NP_115997.5). |
| Immunogen Sequence: |
MTSINGEKAQELGSSATPTK KTVPFKRGVRRGDVLLMVAK LDPDSAKPEKTHPHDAPPCK TSPPATDTGKEKKGETSRTP CGSQASTEILAPKAEKTRTG GLGDPGQGTVALKKGEEGQS IVGKGLGTPKTTELKEAEPQ GKDRQGTRPQAQGPGEGVRP GKAEKEGAEPTNTVEKGNVS KDVGSEGKHVRPQIPGRKWG GFLGRRSKWDGPQNKKDKEG VLLSKAEKTGEPQTQMEKT |
| Tissue Specificity | Selectively expressed in cardiac and skeletal muscles. Weakly expressed in testis, pancreas, placenta, prostate, lung and thymus. |
| Function | May be involved in intracellular trafficking of the muscle cell when in the cytoplasm, whereas entering the nucleus, may be involved in the regulation of muscle specific genes. May play a role in the control of tumor development and progression.restored MYO18B expression in lung cancer cells suppresses anchorage-independent growth. |
| Protein Name | Unconventional Myosin-Xviiib |
| Cellular Localisation | CytoplasmNucleusMyofibrilSarcomerePunctate Pattern In Undifferentiated MyoblastsNuclearOn Primary Cardiomyocytes And Adult MuscleA Partial Sarcomeric Location Was Found In Some Cardiomyocytes |
| Alternative Antibody Names | Anti-Unconventional Myosin-Xviiib antibodyAnti-MYO18B antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
