Immunohistochemical analysis of paraffin-embedded human Squamous cell carcinoma of lung. 1, Antibody was diluted at 1:200 (4°C overnight). 2, Tris-EDTA, pH9.0 was used for antigen retrieval. 3, Secondary antibody was diluted at 1:200 (room temperature, 45min).

Anti-MYO16 antibody (1050-1130) (STJ94316)

SKU:
STJ94316
£48.00 - £252.00
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Host: Rabbit
Applications: WB/ELISA/IHC
Reactivity: Human/Rat/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Rabbit polyclonal antibody anti-Unconventional myosin-XVI (1050-1130) is suitable for use in Western Blot, ELISA and Immunohistochemistry research applications.
Clonality : Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-2000
IHC-p 1:50-300
ELISA 2000-20000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: MYO16
Gene ID: 23026
Uniprot ID: MYO16_HUMAN
Immunogen Region: 1050-1130
Specificity: Myosin XVI Polyclonal Antibody detects endogenous levels of Myosin XVI protein.
Immunogen: Synthesized peptide derived from Myosin XVI. at AA range: 1050-1130
Post Translational Modifications Phosphorylated on tyrosine residues by FYN upon stimulation with CNTN5.
Function Myosins are actin-based motor molecules with ATPase activity. Unconventional myosins serve in intracellular movements. Their highly divergent tails are presumed to bind to membranous compartments, which would be moved relative to actin filaments. May be involved in targeting of the catalytic subunit of protein phosphatase 1 during brain development. Activates PI3K and concomitantly recruits the WAVE1 complex to the close vicinity of PI3K and regulates neuronal morphogenesis.
Protein Name Unconventional Myosin-Xvi
Neuronal Tyrosine-Phosphorylated Phosphoinositide-3-Kinase Adapter 3
Unconventional Myosin-16
Cellular Localisation Cytoplasm
Found In Puncta In Soma And Processes Of Astrocytes And Dissociated Cerebellar Cells With The Morphology Of Migrating Granule Cells
Alternative Antibody Names Anti-Unconventional Myosin-Xvi antibody
Anti-Neuronal Tyrosine-Phosphorylated Phosphoinositide-3-Kinase Adapter 3 antibody
Anti-Unconventional Myosin-16 antibody
Anti-MYO16 antibody
Anti-KIAA0865 antibody
Anti-MYO16B antibody
Anti-NYAP3 antibody

Information sourced from Uniprot.org

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