| Host: | Rabbit |
| Applications: | WB/IF/ICC/ELISA |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000IF/ICC:1:50-1:100ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | MYLK3 |
| Gene ID: | 91807 |
| Uniprot ID: | MYLK3_HUMAN |
| Immunogen Region: | 100-200 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 100-200 of human MYLK3 (NP_872299.2). |
| Immunogen Sequence: | MQQDAAQHGARLEALFRMVA AVDRAIALVGATFQKSKVAD FLMQGRVPWRRGSPGDSPEE NKERVEEEGGKPKHVLSTSG VQSDAREPGEESQKADVLEG T |
| Tissue Specificity | Restricted to heart. |
| Post Translational Modifications | Phosphorylated on serine residues. |
| Function | Kinase that phosphorylates MYL2 in vitro. Promotes sarcomere formation in cardiomyocytes and increases cardiomyocyte contractility. |
| Protein Name | Myosin Light Chain Kinase 3Cardiac-Mybp-C-Associated Ca/Cam KinaseCardiac-Mlck |
| Cellular Localisation | Cytoplasm |
| Alternative Antibody Names | Anti-Myosin Light Chain Kinase 3 antibodyAnti-Cardiac-Mybp-C-Associated Ca/Cam Kinase antibodyAnti-Cardiac-Mlck antibodyAnti-MYLK3 antibodyAnti-MLCK antibody |
Information sourced from Uniprot.org