Host: | Rabbit |
Applications: | WB/IF/ICC/ELISA |
Reactivity: | Human/Mouse |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Clonality : | Polyclonal |
Conjugation: | Unconjugated |
Isotype: | IgG |
Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
Purification: | Affinity purification |
Concentration: | Lot specific |
Dilution Range: | WB:1:500-1:2000IF/ICC:1:50-1:100ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: | MYLK3 |
Gene ID: | 91807 |
Uniprot ID: | MYLK3_HUMAN |
Immunogen Region: | 100-200 |
Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 100-200 of human MYLK3 (NP_872299.2). |
Immunogen Sequence: | MQQDAAQHGARLEALFRMVA AVDRAIALVGATFQKSKVAD FLMQGRVPWRRGSPGDSPEE NKERVEEEGGKPKHVLSTSG VQSDAREPGEESQKADVLEG T |
Tissue Specificity | Restricted to heart. |
Post Translational Modifications | Phosphorylated on serine residues. |
Function | Kinase that phosphorylates MYL2 in vitro. Promotes sarcomere formation in cardiomyocytes and increases cardiomyocyte contractility. |
Protein Name | Myosin Light Chain Kinase 3Cardiac-Mybp-C-Associated Ca/Cam KinaseCardiac-Mlck |
Cellular Localisation | Cytoplasm |
Alternative Antibody Names | Anti-Myosin Light Chain Kinase 3 antibodyAnti-Cardiac-Mybp-C-Associated Ca/Cam Kinase antibodyAnti-Cardiac-Mlck antibodyAnti-MYLK3 antibodyAnti-MLCK antibody |
Information sourced from Uniprot.org