| Host: | Mouse |
| Applications: | IHC-P |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Mouse monoclonal antibody anti-MYH11 is suitable for use in Immunohistochemistry research applications. |
| Clonality : | Monoclonal |
| Clone ID : | SMMS‐1 |
| Conjugation: | Unconjugated |
| Isotype: | IgG1/Kappa |
| Formulation: | Tris-HCI buffer containing stabilizing protein (BSA) and <0.1% ProClin |
| Purification: | Affinity purified |
| Dilution Range: | 1:100‐200 |
| Storage Instruction: | Store at 2‐8°C for up to 24 months. Predilute: Ready to use, no reconstitution necessary. Concentrate: Use dilution range and appropriate lab‐standardized diluent. Stability after dilution: 7 days at 24°C, 3 months at 2‐8°C, 6months at ‐20°C. |
| Gene Symbol: | MYH11 |
| Gene ID: | 4629 |
| Uniprot ID: | MYH11_HUMAN |
| Specificity: | Positive control: Transitional cell carcinoma |
| Immunogen: | Crude human uterus extract |
| Tissue Specificity | Smooth muscle.expressed in the umbilical artery, bladder, esophagus and trachea. Isoform 1 is mostly found in slowly contracting tonic muscles. |
| Function | Muscle contraction. |
| Protein Name | Myosin-11 Myosin Heavy Chain 11 Myosin Heavy Chain - Smooth Muscle Isoform Smmhc |
| Database Links | Reactome: R-HSA-3928663 Reactome: R-HSA-416572 Reactome: R-HSA-445355 Reactome: R-HSA-5625740 Reactome: R-HSA-5625900 Reactome: R-HSA-5627117 Reactome: R-HSA-5627123 |
| Cellular Localisation | Melanosome Identified By Mass Spectrometry In Melanosome Fractions From Stage I To Stage Iv Thick Filaments Of The Myofibrils |
| Alternative Antibody Names | Anti-Myosin-11 antibody Anti-Myosin Heavy Chain 11 antibody Anti-Myosin Heavy Chain - Smooth Muscle Isoform antibody Anti-Smmhc antibody Anti-MYH11 antibody Anti-KIAA0866 antibody |
Information sourced from Uniprot.org