Anti-MYH11 antibody (1160-1313) [S8MR] (STJ11101988)

Name: Anti-MYH11 antibody (1160-1313) [S8MR] (STJ11101988)
SKU: STJ11101988
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⇓ Datasheet ⇓ SDS

SPECIFICATIONS

ClonalityMonoclonal

HostRabbit

ConjugationUnconjugated

IsotypeIgG

STJ11101988

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Short Description	Rabbit monoclonal MYH11 (1160-1313) antibody for use in WB, IHC-P, IF, ICC and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents.
Applications	WB/IHC-P/IF/ICC/ELISA
Host	Rabbit
Reactivity	Human/Mouse/Rat
Note	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Clonality	Monoclonal
Clone ID	S8MR
Isotype	IgG
Conjugation	Unconjugated
Concentration	Lot specific
Purification	Affinity purification
Dilution Range	WB:1:500-1:1000 IHC-P:1:500-1:5000 IF/ICC:1:400-1:1600 ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
Formulation	PBS with 0.05% Proclin300, 0.05% BSA, 50% Glycerol, pH 7.3.
Storage Instruction	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Gene Symbol	MYH11
Gene ID	4629
Uniprot ID	MYH11_HUMAN
Immunogen Region	1160-1313
Immunogen Sequence	DSTATQQELRAKREQEVTVL KKALDEETRSHEAQVQEMRQ KHAQAVEELTEQLEQFKRAK ANLDKNKQTLEKENADLAGE LRVLGQAKQEVEHKKKKLEA QVQELQSKCSDGERARAELN DKVHKLQNEVESVTGMLNEA EGKAIKLAKDVASL
Specificity	Recombinant fusion protein containing a sequence corresponding to amino acids 1160-1313 of human SMMHC/MYH11 (NP_002465.1).

Tissue Specificity	Smooth muscle.expressed in the umbilical artery, bladder, esophagus and trachea. Isoform 1 is mostly found in slowly contracting tonic muscles.
Function	Muscle contraction.
Protein Name	Myosin-11 Myosin Heavy Chain 11 Myosin Heavy Chain - Smooth Muscle Isoform Smmhc
Database Links	Reactome: R-HSA-3928663 Reactome: R-HSA-416572 Reactome: R-HSA-445355 Reactome: R-HSA-5625740 Reactome: R-HSA-5625900 Reactome: R-HSA-5627117 Reactome: R-HSA-5627123
Cellular Localisation	Melanosome Identified By Mass Spectrometry In Melanosome Fractions From Stage I To Stage Iv Thick Filaments Of The Myofibrils
Alternative Antibody Names	Anti-Myosin-11 antibody Anti-Myosin Heavy Chain 11 antibody Anti-Myosin Heavy Chain - Smooth Muscle Isoform antibody Anti-Smmhc antibody Anti-MYH11 antibody Anti-KIAA0866 antibody

Information sourced from Uniprot.org