| Host: | Goat |
| Applications: | Pep-ELISA/WB |
| Reactivity: | Human/Mouse/Rat/Dog |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Goat polyclonal antibody anti-Myelin Protein zero (Internal) is suitable for use in ELISA and Western Blot research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Purification: | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Concentration: | 0.5 mg/mL |
| Dilution Range: | Peptide ELISA: antibody detection limit dilution 1:32000.WB: Approx 28kDa band observed in Rat Spinal Cord lysates (calculated MW of 28.5kDa according to Human NP_000521.1 and of 27.7kDa according to Rat NP_058723.1). Recommended concentration: |
| Storage Instruction: | Store at-20°C on receipt and minimise freeze-thaw cycles. |
| Gene Symbol: | MPZ |
| Gene ID: | 4359 |
| Uniprot ID: | MYP0_HUMAN |
| Immunogen Region: | Internal |
| Accession Number: | NP_000521.1 |
| Specificity: | The presence of this PNS protein in Rat Spinal Cord is likely due to contamination with spinal roots during extraction from the animal. |
| Immunogen Sequence: | DHSRSTKAVSEK |
| Post Translational Modifications | N-glycosylated.contains sulfate-substituted glycan. |
| Function | Is an adhesion molecule necessary for normal myelination in the peripheral nervous system. It mediates adhesion between adjacent myelin wraps and ultimately drives myelin compaction. |
| Protein Name | Myelin Protein P0Myelin Peripheral ProteinMppMyelin Protein Zero |
| Database Links | Reactome: R-HSA-9619665 |
| Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane ProteinIsoform L-Mpz: Myelin Membrane |
| Alternative Antibody Names | Anti-Myelin Protein P0 antibodyAnti-Myelin Peripheral Protein antibodyAnti-Mpp antibodyAnti-Myelin Protein Zero antibodyAnti-MPZ antibody |
Information sourced from Uniprot.org