| Host: | Rabbit |
| Applications: | WB/IHC/IF/ELISA |
| Reactivity: | Human/Rat/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-N-cym protein (2-52 aa) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-1:2000 IHC 1:100-1:300 IF 1:200-1:1000 ELISA 1:5000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | MYCNOS |
| Uniprot ID: | NCYM_HUMAN |
| Immunogen Region: | 2-52 aa |
| Specificity: | This antibody detects endogenous levels of human MYCNOS |
| Immunogen: | Synthesized peptide derived from the human MYCNOS at the amino acid range 2-52 |
| Function | Regulates stability of MYCN in neuroblastoma cells by inhibiting GSK3B-mediated MYCN phosphorylation. Inhibits GSK3B activity by promoting its phosphorylation at 'Ser-9'. |
| Protein Name | N-Cym Protein N-Myc Opposite Strand |
| Cellular Localisation | Cytoplasm Nucleus |
| Alternative Antibody Names | Anti-N-Cym Protein antibody Anti-N-Myc Opposite Strand antibody Anti-MYCNOS antibody Anti-CYMN antibody Anti-NCYM antibody |
Information sourced from Uniprot.org