| Host: | Rabbit |
| Applications: | WB |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-Max dimerization protein 1 is suitable for use in Western Blot research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-2000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | MXD1 |
| Gene ID: | 4084 |
| Uniprot ID: | MAD1_HUMAN |
| Specificity: | This antibody detects endogenous levels of MXD1 at Human |
| Immunogen: | Synthesized peptide derived from human MXD1 |
| Function | Component of a transcriptional repressor complex together with MAX. In complex with MAX binds to the core DNA sequence 5'-CACGATG-3'. Antagonizes MYC transcriptional activity by competing with MYC for MAX binding. Binds to the TERT promoter and represses telomerase expression, possibly by interfering with MYC binding. |
| Protein Name | Max Dimerization Protein 1Max Dimerizer 1Protein Mad |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Max Dimerization Protein 1 antibodyAnti-Max Dimerizer 1 antibodyAnti-Protein Mad antibodyAnti-MXD1 antibodyAnti-MAD antibody |
Information sourced from Uniprot.org