STJ73358 (0. 1ยตg/ml) staining of Human Platelets lysate (35ยตg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

Anti-MUNC18C antibody (514-527) (STJ73358)

⇓ Datasheet ⇓ SDS
SPECIFICATIONS
ClonalityPolyclonal
HostGoat
ConjugationUnconjugated
IsotypeIgG
STJ73358-100
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General Information

Short DescriptionGoat polyclonal antibody anti-MUNC18C (514-527) is suitable for use in ELISA and Western Blot research applications.
ApplicationsPep-ELISA/WB
HostGoat
ReactivityHuman/Pig
NoteSTRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Product Properties

ClonalityPolyclonal
IsotypeIgG
ConjugationUnconjugated
Concentration0.5 mg/mL
PurificationPurified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Dilution RangePeptide ELISA: antibody detection limit dilution 1:128000.
WB: Approx 60kDa band observed in Human Platelets lysates (calculated MW of 67.8kDa according to NP_009200.2). Recommended concentration: 0.1-0.3ยตg/ml.
Formulation0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA
Storage InstructionStore at-20ยฐC on receipt and minimise freeze-thaw cycles.

Target Information

Gene SymbolSTXBP3
Gene ID6814
Uniprot IDSTXB3_HUMAN
Accession NumberNP_009200.2
Immunogen Region514-527
Immunogen SequenceRQKPRANYLEDRKN

Additional Info

Post Translational Modifications Phosphorylated by PKC in platelets in response to thrombin stimulation.phosphorylation inhibits binding to STX4.
Function Together with STX4 and VAMP2, may play a role in insulin-dependent movement of GLUT4 and in docking/fusion of intracellular GLUT4-containing vesicles with the cell surface in adipocytes.
Protein Name Syntaxin-Binding Protein 3
Platelet Sec1 Protein
Psp
Protein Unc-18 Homolog 3
Unc18-3
Protein Unc-18 Homolog C
Unc-18c
Database Links Reactome: R-HSA-114516
Reactome: R-HSA-1445148
Cellular Localisation Cytoplasm
Cytosol
Cell Membrane
In Platelets
Predominantly Cytosolic
Low Amounts Membrane-Associated
Alternative Antibody Names Anti-Syntaxin-Binding Protein 3 antibody
Anti-Platelet Sec1 Protein antibody
Anti-Psp antibody
Anti-Protein Unc-18 Homolog 3 antibody
Anti-Unc18-3 antibody
Anti-Protein Unc-18 Homolog C antibody
Anti-Unc-18c antibody
Anti-STXBP3 antibody

Information sourced from Uniprot.org

Citations

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