Anti-MUM1 antibody [IHC627] (STJA0042218)
SPECIFICATIONS
ClonalityMonoclonal
HostMouse
ConjugationUnconjugated
IsotypeIgG1
General Information
| Short Description | Mouse monoclonal anti-MUM1 for use in IHC-p in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | IHC-p |
| Host | Mouse |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | IHC627 |
| Isotype | IgG1 |
| Conjugation | Unconjugated |
| Formulation | Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide |
| Storage Instruction | Store at 2-8°C for up to 1 year. Do not freeze. |
Target Information
| Specificity | Tested and validated on tonsil, diffuse large b-cell lymphoma, plasmacytoma tissue. |
Additional Info
| Background | Multiple Myeloma Oncogene-1 (MUM1) , also known as Interferon Regulatory Factor 4 (IRF4) , is a transcription factor present in a variety of hematolymphoid neoplasms and in malignant melanoma, but is absent from other human tumours. MUM1 expression has been indicated in both pediatric and adult diffuse large B-cell lymphoma (DLBCL) , and, when the immunostaining status of CD10 and Bcl6 is also considered, Anti-MUM1 can be used to sub-distinguish germinal center type DLBCL from the non-germinal center type. Anti-MUM1 stains normal melanocytes, melanocytic nevi, and malignant melanoma in non-hematopoietic tissues, and can also stain other B-cell lymphomas such as lymphoplasmacytic lymphoma, grade 3 follicular lymphoma, primary central nervous system lymphoma, primary mediastinal large B-cell lymphoma, Burkitt-like lymphoma, and classic Hodgkin s lymphoma. |
Information sourced from Uniprot.org