Anti-Mucin 5B antibody [R02-1N5] (STJA0036755)

SKU:
STJA0036755
£133.50 - £281.50
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Host: Rabbit
Applications: WB/FC
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Rabbit monoclonal anti-Mucin 5B for use in WB and FC in Human samples. Datasheet included with dilution recommendations, and related reagents.
Clonality : Monoclonal
Clone ID : R02-1N5
Conjugation: Unconjugated
Isotype: IgG
Formulation: Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purification: Affinity Chromatography
Dilution Range: WB 1:500-1:1000
FC 1:50-1:100
Storage Instruction: Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles.
Gene Symbol: MUC5B
Gene ID: 727897
Uniprot ID: MUC5B_HUMAN
Immunogen: A synthesized peptide derived from human MUC5B
Tissue Specificity Expressed on surface airway epithelia. Expressed mainly in mucous cells of submucosal glands of airway tissues. Highly expressed in the sublingual gland. Also found in submaxillary glands, endocervix, gall bladder, and pancreas.
Post Translational Modifications Highly glycosylated. C-, N- and O-glycosylated. C-mannosylated in the Cys-rich subdomains probably on the first Trp residue of the WXXW motif. Highly O-glycosylated in the Ser/Thr-rich tandem repeat (TR) region. The repeat region is about 59% O-glycosylated with a high abundance of NeuAc(2)Hex(1)HexNac1-ol.
Function Gel-forming mucin that is thought to contribute to the lubricating and viscoelastic properties of whole saliva and cervical mucus.
Protein Name Mucin-5b
Muc-5b
Cervical Mucin
High Molecular Weight Salivary Mucin Mg1
Mucin-5 Subtype B - Tracheobronchial
Sublingual Gland Mucin
Database Links Reactome: R-HSA-5083625
Reactome: R-HSA-5083632
Reactome: R-HSA-5083636
Reactome: R-HSA-5621480
Reactome: R-HSA-913709
Reactome: R-HSA-977068
Cellular Localisation Secreted
Alternative Antibody Names Anti-Mucin-5b antibody
Anti-Muc-5b antibody
Anti-Cervical Mucin antibody
Anti-High Molecular Weight Salivary Mucin Mg1 antibody
Anti-Mucin-5 Subtype B - Tracheobronchial antibody
Anti-Sublingual Gland Mucin antibody
Anti-MUC5B antibody
Anti-MUC5 antibody

Information sourced from Uniprot.org