| Host: | Rabbit |
| Applications: | IHC/IF |
| Reactivity: | Human/Rat/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-Mucin-5B (1810-1890 aa) is suitable for use in Immunohistochemistry and Immunofluorescence research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | IHC-P 1:50-300IF 1:50-200 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | MUC5B |
| Gene ID: | 727897 |
| Uniprot ID: | MUC5B_HUMAN |
| Immunogen Region: | 1810-1890 aa |
| Specificity: | MUC5B Polyclonal Antibody detects endogenous levels of protein. |
| Immunogen: | Synthesized peptide derived from the human protein at the amino acid range 1810-1890 |
| Post Translational Modifications | Highly glycosylated. C-, N- and O-glycosylated. C-mannosylated in the Cys-rich subdomains probably on the first Trp residue of the WXXW motif. Highly O-glycosylated in the Ser/Thr-rich tandem repeat (TR) region. The repeat region is about 59% O-glycosylated with a high abundance of NeuAc(2)Hex(1)HexNac1-ol. |
| Function | Gel-forming mucin that is thought to contribute to the lubricating and viscoelastic properties of whole saliva and cervical mucus. |
| Protein Name | Mucin-5bMuc-5bCervical MucinHigh Molecular Weight Salivary Mucin Mg1Mucin-5 Subtype B - TracheobronchialSublingual Gland Mucin |
| Database Links | Reactome: R-HSA-5083625Reactome: R-HSA-5083632Reactome: R-HSA-5083636Reactome: R-HSA-5621480Reactome: R-HSA-913709Reactome: R-HSA-977068 |
| Cellular Localisation | Secreted |
| Alternative Antibody Names | Anti-Mucin-5b antibodyAnti-Muc-5b antibodyAnti-Cervical Mucin antibodyAnti-High Molecular Weight Salivary Mucin Mg1 antibodyAnti-Mucin-5 Subtype B - Tracheobronchial antibodyAnti-Sublingual Gland Mucin antibodyAnti-MUC5B antibodyAnti-MUC5 antibody |
Information sourced from Uniprot.org
