Anti-MUC13 antibody (421-470) (STJ94286)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenThe antiserum was produced against synthesized peptide derived from human MUC13. AA range:421-470
General Information
| Short Description | Rabbit polyclonal anti-Mucin-13 (421-470) for use in WB, IHC, IF and ELISA in Human, Rat and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC/IF/ELISA |
| Host | Rabbit |
| Reactivity | Human/Rat/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-1:2000IHC 1:100-1:300IF 1:200-1:1000ELISA 1:20000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | MUC13 |
| Gene ID | 56667 |
| Uniprot ID | MUC13_HUMAN |
| Immunogen | The antiserum was produced against synthesized peptide derived from human MUC13. AA range:421-470 |
| Immunogen Region | 421-470 |
| Specificity | Mucin 13 Polyclonal Antibody detects endogenous levels of Mucin 13 protein. |
Additional Info
| Tissue Specificity | Highly expressed in epithelial tissues, particularly those of the gastrointestinal and respiratory tracts, such as large intestine and trachea, followed by kidney, small intestine, appendix and stomach. |
| Post Translational Modifications | Cleaved into two subunits, alpha and beta, probably between the first EGF domain and the SEA domain. Beta subunit contains the cytoplasmic tail and alpha subunit the extracellular tail. The homooligomerization into dimers is dependent on intrachain disulfide bonds. Highly N-glycosylated. |
| Function | Epithelial and hemopoietic transmembrane mucin that may play a role in cell signaling. |
| Protein Name | Mucin-13Muc-13Down-Regulated In Colon Cancer 1 |
| Database Links | Reactome: R-HSA-5083625Reactome: R-HSA-5083632Reactome: R-HSA-5083636Reactome: R-HSA-5621480Reactome: R-HSA-913709Reactome: R-HSA-9696264Reactome: R-HSA-9696270Reactome: R-HSA-9696273Reactome: R-HSA-977068 |
| Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane ProteinApical Cell MembraneSecretedAlso Exists As A Soluble Form |
| Alternative Antibody Names | Anti-Mucin-13 antibodyAnti-Muc-13 antibodyAnti-Down-Regulated In Colon Cancer 1 antibodyAnti-MUC13 antibodyAnti-DRCC1 antibodyAnti-RECC antibodyAnti-UNQ6194 antibodyAnti-PRO20221 antibody |
Information sourced from Uniprot.org