Host: |
Rabbit |
Applications: |
WB/IHC/IF/ELISA |
Reactivity: |
Human/Rat/Mouse |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Rabbit polyclonal antibody anti-Mucin-13 (421-470) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications. |
Clonality: |
Polyclonal |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Concentration: |
1 mg/mL |
Dilution Range: |
WB 1:500-1:2000IHC 1:100-1:300IF 1:200-1:1000ELISA 1:20000 |
Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: |
MUC13 |
Gene ID: |
56667 |
Uniprot ID: |
MUC13_HUMAN |
Immunogen Region: |
421-470 |
Specificity: |
Mucin 13 Polyclonal Antibody detects endogenous levels of Mucin 13 protein. |
Immunogen: |
The antiserum was produced against synthesized peptide derived from human MUC13. AA range:421-470 |
Tissue Specificity | Highly expressed in epithelial tissues, particularly those of the gastrointestinal and respiratory tracts, such as large intestine and trachea, followed by kidney, small intestine, appendix and stomach. |
Post Translational Modifications | Cleaved into two subunits, alpha and beta, probably between the first EGF domain and the SEA domain. Beta subunit contains the cytoplasmic tail and alpha subunit the extracellular tail. The homooligomerization into dimers is dependent on intrachain disulfide bonds. Highly N-glycosylated. |
Function | Epithelial and hemopoietic transmembrane mucin that may play a role in cell signaling. |
Protein Name | Mucin-13Muc-13Down-Regulated In Colon Cancer 1 |
Database Links | Reactome: R-HSA-5083625Reactome: R-HSA-5083632Reactome: R-HSA-5083636Reactome: R-HSA-5621480Reactome: R-HSA-913709Reactome: R-HSA-9696264Reactome: R-HSA-9696270Reactome: R-HSA-9696273Reactome: R-HSA-977068 |
Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane ProteinApical Cell MembraneSecretedAlso Exists As A Soluble Form |
Alternative Antibody Names | Anti-Mucin-13 antibodyAnti-Muc-13 antibodyAnti-Down-Regulated In Colon Cancer 1 antibodyAnti-MUC13 antibodyAnti-DRCC1 antibodyAnti-RECC antibodyAnti-UNQ6194 antibodyAnti-PRO20221 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance