| Applications: | WB/IF/ICC/ELISA |
| Host: | Rabbit |
| Reactivity: | Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | Lot specific |
| Purification: | Affinity purification |
| Dilution Range: | WB:1:500-1:2000IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation: | PBS with 0.05% Proclin300, 50% Glycerol, pH 7.3. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | MTTP |
| Gene ID: | 4547 |
| Uniprot ID: | MTP_HUMAN |
| Immunogen Region: | 590-894 |
| Immunogen Sequence: | NNPSYMDVKNILLSIGELPQ EMNKYMLAIVQDILRFEMPA SKIVRRVLKEMVAHNYDRFS RSGSSSAYTGYIERSPRSAS TYSLDILYSGSGILRRSNLN IFQYIGKAGLHGSQVVIEAQ GLEALIAATPDEGEENLDSY AGMSAILFDVQLRPVTFFNG YSDLMSKMLSASGDPISVVK GLILLIDHSQELQLQSGLKA NIEVQGGLAIDISGAMEFSL WYRESKTRVKNRVTVVITT |
| Specificity: | A synthetic peptide corresponding to a sequence within amino acids 550-650 of human MTTP (NP_000244.2). |
| Tissue Specificity | Liver and small intestine. Also found in ovary, testis and kidney. |
| Function | Catalyzes the transport of triglyceride, cholesteryl ester, and phospholipid between phospholipid surfaces. Required for the assembly and secretion of plasma lipoproteins that contain apolipoprotein B. May be involved in regulating cholesteryl ester biosynthesis in cells that produce lipoproteins. |
| Protein Name | Microsomal Triglyceride Transfer Protein Large Subunit |
| Database Links | Reactome: R-HSA-8866423Reactome: R-HSA-8963888Reactome: R-HSA-8964041 |
| Cellular Localisation | Endoplasmic ReticulumGolgi ApparatusColocalizes With P4hb/Pdi In The Endoplasmic Reticulum |
| Alternative Antibody Names | Anti-Microsomal Triglyceride Transfer Protein Large Subunit antibodyAnti-MTTP antibodyAnti-MTP antibody |
Information sourced from Uniprot.org
