• Western blot analysis of lysates from 3T3 cells, primary antibody was diluted at 1:1000, 4°C over night

Anti-MTPAP antibody (445-495 aa) (STJ194598)

SKU:
STJ194598

Current Stock:
Host: Rabbit
Applications: WB
Reactivity: Human/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-PolyA RNA polymerase, mitochondrial (445-495 aa) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: MTPAP
Gene ID: 55149
Uniprot ID: PAPD1_HUMAN
Immunogen Region: 445-495 aa
Specificity: This antibody detects endogenous levels of PAPD1 at Human/Mouse
Immunogen: Synthesized peptide derived from the human PAPD1 at the amino acid range 445-495
Function Polymerase that creates the 3' poly(A) tail of mitochondrial transcripts. Can use all four nucleotides, but has higher activity with ATP and UTP (in vitro). Plays a role in replication-dependent histone mRNA degradation. May be involved in the terminal uridylation of mature histone mRNAs before their degradation is initiated. Might be responsible for the creation of some UAA stop codons which are not encoded in mtDNA.
Protein Name Poly(A Rna Polymerase - Mitochondrial
Pap
Pap-Associated Domain-Containing Protein 1
Polynucleotide Adenylyltransferase
Terminal Uridylyltransferase 1
Tutase 1
Mtpap
Cellular Localisation Cytoplasm
Mitochondrion
Alternative Antibody Names Anti-Poly(A Rna Polymerase - Mitochondrial antibody
Anti-Pap antibody
Anti-Pap-Associated Domain-Containing Protein 1 antibody
Anti-Polynucleotide Adenylyltransferase antibody
Anti-Terminal Uridylyltransferase 1 antibody
Anti-Tutase 1 antibody
Anti-Mtpap antibody
Anti-MTPAP antibody
Anti-PAPD1 antibody

Information sourced from Uniprot.org

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