Anti-MTMR2 antibody (STJA0009571)

SKU:
STJA0009571
£49.00 - £261.00
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Short Description :Rabbit polyclonal anti-Myotubularin-related protein 2 for use in WB in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents.
Applications:WB
Host:Rabbit
Reactivity:Human/Mouse
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality :Polyclonal
Isotype:IgG
Conjugation:Unconjugated
Concentration:1 mg/mL
Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Dilution Range:WB 1:500-2000
Formulation:Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Storage Instruction:Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol:MTMR2
Gene ID:8898
Uniprot ID:MTMR2_HUMAN
Immunogen:Synthesized peptide derived from human MTMR2
Specificity:This antibody detects endogenous levels of MTMR2 at Human, Mouse
Function Lipid phosphatase that specifically dephosphorylates the D-3 position of phosphatidylinositol 3-phosphate and phosphatidylinositol 3,5-bisphosphate, generating phosphatidylinositol and phosphatidylinositol 5-phosphate. Regulates the level of these phosphoinositides critical for various biological processes including autophagy initiation and autophagosome maturation.
Protein Name Phosphatidylinositol-3 -5-Bisphosphate 3-Phosphatase Mtmr2
Myotubularin-Related Protein 2
Phosphatidylinositol-3-Phosphate Phosphatase
Database Links Reactome: R-HSA-1483248
Reactome: R-HSA-1660499
Reactome: R-HSA-1660516
Reactome: R-HSA-1660517
Cellular Localisation Cytoplasm
Early Endosome Membrane
Peripheral Membrane Protein
Perinuclear Region
Cell Projection
Axon
Endosome Membrane
Partly Associated With Membranes
Localizes To Vacuoles In Hypo-Osmotic Conditions
Alternative Antibody Names Anti-Phosphatidylinositol-3 -5-Bisphosphate 3-Phosphatase Mtmr2 antibody
Anti-Myotubularin-Related Protein 2 antibody
Anti-Phosphatidylinositol-3-Phosphate Phosphatase antibody
Anti-MTMR2 antibody
Anti-KIAA1073 antibody

Information sourced from Uniprot.org