• STJ70068 (1µg/ml) staining of Human Skeletal Muscle lysate (35µg protein in RIPA buffer). Detected by chemiluminescence.
  • STJ70068 (1µg/ml) staining of HepG2 cell lysate (35µg protein in RIPA buffer). Detected by chemiluminescence.
  • STJ70068 (1µg/ml) staining of Mouse Skeletal Muscle lysate (35µg protein in RIPA buffer). Detected by chemiluminescence.

Anti-MTM1 antibody (C-Term) (STJ70068)

SKU:
STJ70068-100

£312.50
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Host: Goat
Applications: Pep-ELISA/WB/IHC
Reactivity: Human/Mouse/Dog/Cow
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Goat polyclonal antibody anti-MTM1 (C-Term) is suitable for use in ELISA, Western Blot and Immunohistochemistry research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA
Purification: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Concentration: 0.5 mg/mL
Dilution Range: Peptide ELISA: antibody detection limit dilution 1:16000.
WB: Approx 70kDa band observed in lysates of Human and Mouse Skeletal Muscle and of cell line HepG2 (calculated MW of 69.9kDa according to NP_000243.1and 69.6kDa according to Mouse NP_0011
Storage Instruction: Store at-20°C on receipt and minimise freeze-thaw cycles.
Gene Symbol: MTM1
Gene ID: 4534
Uniprot ID: MTM1_HUMAN
Immunogen Region: C-Term
Accession Number: NP_000243.1
Immunogen Sequence: SSPSQMMPHVQTHF
Protein Name Myotubularin
Phosphatidylinositol-3 -5-Bisphosphate 3-Phosphatase
Phosphatidylinositol-3-Phosphate Phosphatase
Database Links Reactome: R-HSA-1660499
Reactome: R-HSA-1660516
Reactome: R-HSA-1660517
Cellular Localisation Cytoplasm
Cell Membrane
Peripheral Membrane Protein
Cell Projection
Filopodium
Ruffle
Late Endosome
Myofibril
Sarcomere
Localizes As A Dense Cytoplasmic Network
Also Localizes To The Plasma Membrane
Including Plasma Membrane Extensions Such As Filopodia And Ruffles
Predominantly Located In The Cytoplasm Following Interaction With Mtmr12
Recruited To The Late Endosome Following Egf Stimulation
In Skeletal Muscles
Co-Localizes With Mtmr12 In The Sarcomere
Alternative Antibody Names Anti-Myotubularin antibody
Anti-Phosphatidylinositol-3 -5-Bisphosphate 3-Phosphatase antibody
Anti-Phosphatidylinositol-3-Phosphate Phosphatase antibody
Anti-MTM1 antibody
Anti-CG2 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance