| Applications: | WB/ELISA |
| Host: | Rabbit |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | Lot specific |
| Purification: | Affinity purification |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | MTIF3 |
| Gene ID: | 219402 |
| Uniprot ID: | IF3M_HUMAN |
| Immunogen Region: | 1-278 |
| Immunogen Sequence: | MAALFLKRLTLQTVKSENSC IRCFGKHILQKTAPAQLSPI ASAPRLSFLIHAKAFSTAED TQNEGKKTKKNKTAFSNVGR KISQRVIHLFDEKGNDLGNM HRANVIRLMDERDLRLVQRN TSTEPAEYQLMTGLQILQER QRLREMEKANPKTGPTLRKE LILSSNIGQHDLDTKTKQIQ QWIKKKHLVQITIKKGKNVD VSENEMEEIFHQILQTMPGI ATFSSRPQAVQGGKALMCV |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-278 of human MTIF3 (NP_690876.3). |
| Function | IF-3 binds to the 28S ribosomal subunit and shifts the equilibrium between 55S ribosomes and their 39S and 28S subunits in favor of the free subunits, thus enhancing the availability of 28S subunits on which protein synthesis initiation begins. |
| Protein Name | Translation Initiation Factor If-3 - MitochondrialIf-3(MtIf-3mtIf3(MtIf3mt |
| Database Links | Reactome: R-HSA-5368286 |
| Cellular Localisation | Mitochondrion |
| Alternative Antibody Names | Anti-Translation Initiation Factor If-3 - Mitochondrial antibodyAnti-If-3(Mt antibodyAnti-If-3mt antibodyAnti-If3(Mt antibodyAnti-If3mt antibodyAnti-MTIF3 antibodyAnti-DC38 antibody |
Information sourced from Uniprot.org
