| Host: | Rabbit |
| Applications: | WB/IHC-P/IF/ICC/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000IHC-P:1:50-1:100IF/ICC:1:50-1:100ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | MTIF2 |
| Gene ID: | 4528 |
| Uniprot ID: | IF2M_HUMAN |
| Immunogen Region: | 428-727 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 428-727 of human MTIF2 (NP_002444.2). |
| Immunogen Sequence: | GEEILEVESEPRAREVVDWR KYEQEQEKGQEDLKIIEEKR KEHKEAHQKAREKYGHLLWK KRSILRFLERKEQIPLKPKE KRERDSNVLSVIIKGDVDGS VEAILNIIDTYDASHECELE LVHFGVGDVSANDVNLAETF DGVIYGFNVNAGNVIQQSAA KKGVKIKLHKIIYRLVEDLQ EELSSRLPCAVEEHPVGEAS ILATFSVTEGKKKVPVAGCR VQKGQLEKQKKFKLTRNGH |
| Tissue Specificity | Expressed in all tissues examined. Highest level in skeletal muscle. |
| Function | One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex. |
| Protein Name | Translation Initiation Factor If-2 - MitochondrialIf-2(MtIf-2mtIf2(Mt |
| Database Links | Reactome: R-HSA-5368286 |
| Cellular Localisation | Mitochondrion |
| Alternative Antibody Names | Anti-Translation Initiation Factor If-2 - Mitochondrial antibodyAnti-If-2(Mt antibodyAnti-If-2mt antibodyAnti-If2(Mt antibodyAnti-MTIF2 antibody |
Information sourced from Uniprot.org