Anti-MTHFR antibody [R02-6H3] (STJA0034588)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenRecombinant protein of human MTHFR
General Information
| Short Description | Rabbit monoclonal anti-MTHFR for use in WB, ICC, IF and IP in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ICC/IF/IP |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | R02-6H3 |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 0.3 mg/mL |
| Purification | Affinity Purified |
| Dilution Range | WB 1:500-1:1000IF 1:50-1:200IP 1:20 |
| Formulation | 50mM Tris-Glycine (pH 7.4) , 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA |
| Storage Instruction | Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles. |
Target Information
| Gene Symbol | MTHFR |
| Gene ID | 4524 |
| Uniprot ID | MTHR_HUMAN |
| Immunogen | Recombinant protein of human MTHFR |
Additional Info
| Post Translational Modifications | Phosphorylation of an N-terminal serine-rich phosphorylation region increases sensitivity to S-adenosylmethionine and inhibition. |
| Function | Catalyzes the conversion of 5,10-methylenetetrahydrofolate to 5-methyltetrahydrofolate, a cosubstrate for homocysteine remethylation to methionine. Represents a key regulatory connection between the folate and methionine cycles (Probable). |
| Protein Name | Methylenetetrahydrofolate ReductaseNadph |
| Database Links | Reactome: R-HSA-196757 |
| Cellular Localisation | |
| Alternative Antibody Names | Anti-Methylenetetrahydrofolate Reductase antibodyAnti-Nadph antibodyAnti-MTHFR antibody |
Information sourced from Uniprot.org