Function | Microtubule-associated factor involved in the late phase of epithelial polarization and microtubule dynamics regulation. Plays a role in the development and maintenance of non-centrosomal microtubule bundles at the lateral membrane in polarized epithelial cells. Required for faithful chromosome segregation during mitosis. |
Protein Name | Microtubule Cross-Linking Factor 1Coiled-Coil Domain-Containing Protein 165Par-1-Interacting ProteinSoga Family Member 2 |
Cellular Localisation | Lateral Cell MembraneApical Cell MembraneCytoplasmCytoskeletonSpindle PoleMidbodyColocalized With Microtubules At The Base Of CiliaGradually Accumulates On The Apicobasal Microtubule Bundles During Epithelial Cell PolarizationColocalized With The Apicobasal Microtubule Bundles Running Beneath The Lateral MembraneColocalized With Microtubule Bundles In The Spindle Pole In Mitotic Cells And In The Midbodies At The End Of Cytokinesis |
Alternative Antibody Names | Anti-Microtubule Cross-Linking Factor 1 antibodyAnti-Coiled-Coil Domain-Containing Protein 165 antibodyAnti-Par-1-Interacting Protein antibodyAnti-Soga Family Member 2 antibodyAnti-MTCL1 antibodyAnti-CCDC165 antibodyAnti-KIAA0802 antibodyAnti-SOGA2 antibody |
Information sourced from Uniprot.org