• Western blot analysis of various lysates, using MSR1 rabbit polyclonal antibody (STJ24620) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% non-fat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 60s.
  • Immunofluorescence analysis of human lung cells using MSR1 rabbit polyclonal antibody (STJ24620) at dilution of 1:200 (40x lens). Blue: DAPI for nuclear staining.
  • Immunofluorescence analysis of mouse lung cells using MSR1 rabbit polyclonal antibody (STJ24620) at dilution of 1:200 (40x lens). Blue: DAPI for nuclear staining.

Anti-MSR1 antibody (90-274) (STJ24620)

SKU:
STJ24620

£112.50 - £522.50
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Host: Rabbit
Applications: WB/IF
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-MSR1 (90-274) is suitable for use in Western Blot and Immunofluorescence research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:1000
IF/ICC 1:50-1:200
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: MSR1
Gene ID: 4481
Uniprot ID: MSRE_HUMAN
Immunogen Region: 90-274
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 90-274 of human MSR1 (NP_619729.1).
Immunogen Sequence: ANDITQSLTGKGNDSEEEMR FQEVFMEHMSNMEKRIQHIL DMEANLMDTEHFQNFSMTTD QRFNDILLQLSTLFSSVQGH GNAIDEISKSLISLNTTLLD LQLNIENLNGKIQENTFKQQ EEISKLEERVYNVSAEIMAM KEEQVHLEQEIKGEVKVLNN ITNDLRLKDWEHSQTLRNIT LIQGP
Tissue Specificity Isoform I, isoform II and isoform III are expressed in monocyte-derived macrophages. Isoform I and isoform II are expressed in the liver, placenta and brain.
Function Membrane glycoproteins implicated in the pathologic deposition of cholesterol in arterial walls during atherogenesis. Two types of receptor subunits exist. These receptors mediate the endocytosis of a diverse group of macromolecules, including modified low density lipoproteins (LDL). Isoform III does not internalize acetylated LDL.
Protein Name Macrophage Scavenger Receptor Types I And Ii
Macrophage Acetylated Ldl Receptor I And Ii
Scavenger Receptor Class A Member 1
Cd Antigen Cd204
Database Links Reactome: R-HSA-3000480
Cellular Localisation Membrane
Single-Pass Type Ii Membrane Protein
Alternative Antibody Names Anti-Macrophage Scavenger Receptor Types I And Ii antibody
Anti-Macrophage Acetylated Ldl Receptor I And Ii antibody
Anti-Scavenger Receptor Class A Member 1 antibody
Anti-Cd Antigen Cd204 antibody
Anti-MSR1 antibody
Anti-SCARA1 antibody

Information sourced from Uniprot.org

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