Anti-MSI1 antibody (200-362) (STJ111162)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal MSI1 (200-362) antibody for use in WB, IHC-P and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC-P/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:1000IHC-P:1:50-1:100ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.09% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | MSI1 |
| Gene ID | 4440 |
| Uniprot ID | MSI1H_HUMAN |
| Immunogen Region | 200-362 |
| Immunogen Sequence | SRVMPYGMDAFMLGIGMLGY PGFQATTYASRSYTGLAPGY TYQFPEFRVERTPLPSAPVL PELTAIPLTAYGPMAAAAAA AAVVRGTGSHPWTMAPPPGS TPSRTGGFLGTTSPGPMAEL YGAANQDSGVSSYISAASPA PSTGFGHSLGGPLIATAFTN GYH |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 200-362 of human Musashi-1 (MSI1) (NP_002433.1). |
Additional Info
| Tissue Specificity | Detected in fetal kidney, brain, liver and lung, and in adult brain and pancreas. Detected in hepatoma cell lines. |
| Function | RNA binding protein that regulates the expression of target mRNAs at the translation level. Regulates expression of the NOTCH1 antagonist NUMB. Binds RNA containing the sequence 5'-GUUAGUUAGUUAGUU-3' and other sequences containing the pattern 5'-GAU(1-3)AGU-3'. May play a role in the proliferation and maintenance of stem cells in the central nervous system. |
| Protein Name | Rna-Binding Protein Musashi Homolog 1Musashi-1 |
| Database Links | Reactome: R-HSA-9010553 |
| Cellular Localisation | CytoplasmNucleus |
| Alternative Antibody Names | Anti-Rna-Binding Protein Musashi Homolog 1 antibodyAnti-Musashi-1 antibodyAnti-MSI1 antibody |
Information sourced from Uniprot.org