| Host: | Rabbit |
| Applications: | WB/IHC-P/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.09% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:1000IHC-P:1:50-1:100ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | MSI1 |
| Gene ID: | 4440 |
| Uniprot ID: | MSI1H_HUMAN |
| Immunogen Region: | 200-362 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 200-362 of human Musashi-1 (MSI1) (NP_002433.1). |
| Immunogen Sequence: | SRVMPYGMDAFMLGIGMLGY PGFQATTYASRSYTGLAPGY TYQFPEFRVERTPLPSAPVL PELTAIPLTAYGPMAAAAAA AAVVRGTGSHPWTMAPPPGS TPSRTGGFLGTTSPGPMAEL YGAANQDSGVSSYISAASPA PSTGFGHSLGGPLIATAFTN GYH |
| Tissue Specificity | Detected in fetal kidney, brain, liver and lung, and in adult brain and pancreas. Detected in hepatoma cell lines. |
| Function | RNA binding protein that regulates the expression of target mRNAs at the translation level. Regulates expression of the NOTCH1 antagonist NUMB. Binds RNA containing the sequence 5'-GUUAGUUAGUUAGUU-3' and other sequences containing the pattern 5'-GAU(1-3)AGU-3'. May play a role in the proliferation and maintenance of stem cells in the central nervous system. |
| Protein Name | Rna-Binding Protein Musashi Homolog 1Musashi-1 |
| Database Links | Reactome: R-HSA-9010553 |
| Cellular Localisation | CytoplasmNucleus |
| Alternative Antibody Names | Anti-Rna-Binding Protein Musashi Homolog 1 antibodyAnti-Musashi-1 antibodyAnti-MSI1 antibody |
Information sourced from Uniprot.org