| Host: | Mouse |
| Applications: | IHC-P |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Mouse monoclonal antibody anti-MS4A1 is suitable for use in Immunohistochemistry research applications. |
| Clonality : | Monoclonal |
| Clone ID : | L26 |
| Conjugation: | Unconjugated |
| Isotype: | IgG2a/Kappa |
| Formulation: | Tris-HCI buffer containing stabilizing protein (BSA) and <0.1% ProClin |
| Purification: | Affinity purified |
| Dilution Range: | 1:100‐300 |
| Storage Instruction: | Store at 2‐8°C for up to 24 months. Predilute: Ready to use, no reconstitution necessary. Concentrate: Use dilution range and appropriate lab‐standardized diluent. Stability after dilution: 7 days at 24°C, 3 months at 2‐8°C, 6months at ‐20°C. |
| Gene Symbol: | MS4A1 |
| Gene ID: | 931 |
| Uniprot ID: | CD20_HUMAN |
| Specificity: | Positive control: Tonsil, lymph node |
| Immunogen: | Human tonsil B cells |
| Tissue Specificity | Expressed on B-cells. |
| Post Translational Modifications | Phosphorylated on serines and threonines in resting B-cells. Protein kinase C/PKC can use CD20 as substrate. |
| Function | B-lymphocyte-specific membrane protein that plays a role in the regulation of cellular calcium influx necessary for the development, differentiation, and activation of B-lymphocytes. Functions as a store-operated calcium (SOC) channel component promoting calcium influx after activation by the B-cell receptor/BCR. |
| Protein Name | B-Lymphocyte Antigen Cd20 B-Lymphocyte Surface Antigen B1 Bp35 Leukocyte Surface Antigen Leu-16 Membrane-Spanning 4-Domains Subfamily A Member 1 Cd Antigen Cd20 |
| Cellular Localisation | Cell Membrane Multi-Pass Membrane Protein Lipid-Anchor Constitutively Associated With Membrane Rafts |
| Alternative Antibody Names | Anti-B-Lymphocyte Antigen Cd20 antibody Anti-B-Lymphocyte Surface Antigen B1 antibody Anti-Bp35 antibody Anti-Leukocyte Surface Antigen Leu-16 antibody Anti-Membrane-Spanning 4-Domains Subfamily A Member 1 antibody Anti-Cd Antigen Cd20 antibody Anti-MS4A1 antibody Anti-CD20 antibody |
Information sourced from Uniprot.org