| Host: | Mouse |
| Applications: | IHC/IF/ELISA |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Mouse monoclonal antibody anti-B-lymphocyte antigen CD20 (EPANPSEKNSPSTQY) is suitable for use in Immunohistochemistry, Immunofluorescence and ELISA research applications. |
| Clonality : | Monoclonal |
| Clone ID : | 3E9D3C1G3 |
| Conjugation: | Unconjugated |
| Formulation: | Liquid in PBS containing 0.03% Sodium Azide, 0.5% BSA, 50% Glycerol. |
| Purification: | Affinity purification |
| Dilution Range: | IHC 1:200-1:1000 IF 1:200-1:1000 ELISA 1:10000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | MS4A1 |
| Gene ID: | 931 |
| Uniprot ID: | CD20_HUMAN |
| Immunogen Region: | EPANPSEKNSPSTQY |
| Specificity: | CD20 Monoclonal Antibody detects endogenous levels of CD20 protein. |
| Immunogen: | Synthetic peptide corresponding to aa (EPANPSEKNSPSTQY) of human CD20, conjugated to KLH. |
| Post Translational Modifications | Phosphorylated on serines and threonines in resting B-cells. Protein kinase C/PKC can use CD20 as substrate. |
| Function | B-lymphocyte-specific membrane protein that plays a role in the regulation of cellular calcium influx necessary for the development, differentiation, and activation of B-lymphocytes. Functions as a store-operated calcium (SOC) channel component promoting calcium influx after activation by the B-cell receptor/BCR. |
| Protein Name | B-Lymphocyte Antigen Cd20 B-Lymphocyte Surface Antigen B1 Bp35 Leukocyte Surface Antigen Leu-16 Membrane-Spanning 4-Domains Subfamily A Member 1 Cd Antigen Cd20 |
| Cellular Localisation | Cell Membrane Multi-Pass Membrane Protein Lipid-Anchor Constitutively Associated With Membrane Rafts |
| Alternative Antibody Names | Anti-B-Lymphocyte Antigen Cd20 antibody Anti-B-Lymphocyte Surface Antigen B1 antibody Anti-Bp35 antibody Anti-Leukocyte Surface Antigen Leu-16 antibody Anti-Membrane-Spanning 4-Domains Subfamily A Member 1 antibody Anti-Cd Antigen Cd20 antibody Anti-MS4A1 antibody Anti-CD20 antibody |
Information sourced from Uniprot.org