Anti-MS4A1 antibody (197-297) (STJ24609)

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STJ24609
£112.50 - £524.50
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Host: Rabbit
Applications: WB/IHC-P/IF/ICC/ELISA
Reactivity: Human/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality : Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3.
Purification: Affinity purification
Concentration: Lot specific
Dilution Range: WB:1:500-1:1000
IHC-P:1:50-1:200
IF/ICC:1:50-1:200
ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: MS4A1
Gene ID: 931
Uniprot ID: CD20_HUMAN
Immunogen Region: 197-297
Specificity: Recombinant fusion protein containing a sequence corresponding to amino acids 197-297 of human CD20 (NP_068769.2).
Immunogen Sequence: MLIFAFFQELVIAGIVENEW KRTCSRPKSNIVLLSAEEKK EQTIEIKEEVVGLTETSSQP KNEEDIEIIPIQEEEEEETE TNFPEPPQDQESSPIENDSS P
Tissue Specificity Expressed on B-cells.
Post Translational Modifications Phosphorylated on serines and threonines in resting B-cells. Protein kinase C/PKC can use CD20 as substrate.
Function B-lymphocyte-specific membrane protein that plays a role in the regulation of cellular calcium influx necessary for the development, differentiation, and activation of B-lymphocytes. Functions as a store-operated calcium (SOC) channel component promoting calcium influx after activation by the B-cell receptor/BCR.
Protein Name B-Lymphocyte Antigen Cd20
B-Lymphocyte Surface Antigen B1
Bp35
Leukocyte Surface Antigen Leu-16
Membrane-Spanning 4-Domains Subfamily A Member 1
Cd Antigen Cd20
Cellular Localisation Cell Membrane
Multi-Pass Membrane Protein
Lipid-Anchor
Constitutively Associated With Membrane Rafts
Alternative Antibody Names Anti-B-Lymphocyte Antigen Cd20 antibody
Anti-B-Lymphocyte Surface Antigen B1 antibody
Anti-Bp35 antibody
Anti-Leukocyte Surface Antigen Leu-16 antibody
Anti-Membrane-Spanning 4-Domains Subfamily A Member 1 antibody
Anti-Cd Antigen Cd20 antibody
Anti-MS4A1 antibody
Anti-CD20 antibody

Information sourced from Uniprot.org