Anti-MRPL58 antibody (7-57 aa) (STJ194879)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from the human ICT1 at the amino acid range 7-57
General Information
| Short Description | Rabbit polyclonal anti-Large ribosomal subunit protein mL62 (7-57 aa) for use in WB in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | MRPL58 |
| Gene ID | 3396 |
| Uniprot ID | ICT1_HUMAN |
| Immunogen | Synthesized peptide derived from the human ICT1 at the amino acid range 7-57 |
| Immunogen Region | 7-57 aa |
| Specificity | This antibody detects endogenous levels of ICT1 at Human/Mouse |
Additional Info
| Post Translational Modifications | Methylation of glutamine in the GGQ triplet by HEMK1. |
| Function | Essential peptidyl-tRNA hydrolase component of the mitochondrial large ribosomal subunit. Acts as a codon-independent translation release factor that has lost all stop codon specificity and directs the termination of translation in mitochondrion, possibly in case of abortive elongation. Involved in the hydrolysis of peptidyl-tRNAs that have been prematurely terminated and thus in the recycling of stalled mitochondrial ribosomes. |
| Protein Name | Large Ribosomal Subunit Protein Ml6239s Ribosomal Protein L58 - MitochondrialMrp-L58Digestion Substraction 1Ds-1Immature Colon Carcinoma Transcript 1 ProteinPeptidyl-Trna Hydrolase Ict1 - Mitochondrial |
| Database Links | Reactome: R-HSA-5368286Reactome: R-HSA-5389840Reactome: R-HSA-5419276 |
| Cellular Localisation | Mitochondrion |
| Alternative Antibody Names | Anti-Large Ribosomal Subunit Protein Ml62 antibodyAnti-39s Ribosomal Protein L58 - Mitochondrial antibodyAnti-Mrp-L58 antibodyAnti-Digestion Substraction 1 antibodyAnti-Ds-1 antibodyAnti-Immature Colon Carcinoma Transcript 1 Protein antibodyAnti-Peptidyl-Trna Hydrolase Ict1 - Mitochondrial antibodyAnti-MRPL58 antibodyAnti-DS1 antibodyAnti-ICT1 antibody |
Information sourced from Uniprot.org